Anti-FcεRIα antibodies, human

Anti-FcεRIα antibodies, human

Clone: CRA1 | Dilution: 1:50
Clone CRA1 detects the α subunit of the human high-affinity Fc receptor for IgE. The receptor is composed of one α-, one β-, and two disulphide-linked γ-chains, of which the α subunit binds IgE1. FcεRIα is expressed on mast and basophil cells, is upregulated in the presence of IgE, and is found on a subset of blood dendritic cells. CRA1 does not inhibit the binding of IgE it induces mast cell activation followed by a histamine release. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.

Alternative names

FCER1A, Fce1a, FcERI

Technical specifications

  • Antigen: FcεRIα
  • Clone: CRA1
  • Isotype: mouse IgG2bκ
  • Isotype control: Mouse IgG2b – isotype control antibodies
  • Alternative names of antigen: FCER1A, Fce1a, FcERI
  • Entrez Gene ID: 2205
  • Molecular mass of antigen [kDa]: 27
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, VioBlue
  • Selected references

    1. Suzukawa, M. et al. (2005) IgE- and FcepsilonRI-mediated migration of human basophils. Int. Immunol. 17: 1249-1255
Product options: 4
for 30
tests
(1)
USD 84.00
for 100
tests
(1)
USD 248.00
for 30
tests
(1)
USD 126.00
for 100
tests
(1)
USD 310.00

Related products

5 products available | view all