Anti-Cytochrome c antibodies, human, mouse, rat

Anti-Cytochrome c antibodies, human, mouse, rat

Clone: REA702 | Dilution: 1:50
Clone REA702 recognizes the human, mouse, and rat cytochrome c, a 15 kDa hemeprotein located in the intermembrane of the mitochondrion. Cytochromes are involved in cell respiration, photosynthesis, and other biochemical reactions. Cytochrome c plays also a role in apoptosis, by release to cytoplasma and binding Apaf-1 which activates procaspase 9. Cytochrome c is found in plants, animals, and many unicellular organisms and catalyzes the electron transfer from reduced cytochrome c to oxygen.
Additional information: Clone REA702 displays negligible binding to Fc receptors.

Alternative names

Cyt c

Technical specifications

  • Antigen: Cytochrome c
  • Clone: REA702
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Cyt c
  • Entrez Gene ID: 54205, 13063, 25309
  • Molecular mass of antigen [kDa]: 12
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Margoliash, E. (1963) Primary structure and evolution of cytochrome c. Proc. Natl. Acad. Sci. U.S.A. 50: 672-679
    2. Ferguson, H. A. et al. (2003) UV-induced apoptosis is mediated independent of caspase-9 in MCF-7 cells: a model for cytochrome c resistance. J. Biol. Chem. 278(46): 45793-45800
    3. Tafani, M. et al. (2002) Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. J. Biol. Chem. 277(12): 10073-10082
Product options: 6
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USD 97.00
for 100
tests
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USD 272.00
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tests
(1)
USD 124.00
for 100
tests
(1)
USD 288.00

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