Anti-PSA-NCAM MicroBead Kit, human and mouse

Anti-PSA-NCAM MicroBead Kit, human and mouse

The Anti-PSA-NCAM MicroBead kit has been designed for the isolation of PSA-NCAM
neural progenitors from differentiated ES or iPS cell cultures.

Background information

The Anti-PSA-NCAM antibody recognizes an epitope on polysialic acid (PSA) which, in vertebrates, is found linked to the extracellular domain of the neural cell adhesion molecule (NCAM, CD56).¹ PSA-NCAM, the highly polysialated form of NCAM, is predominantly expressed
in embryonic and neonatal neural tissue.² In vitro differentiation of human and mouse pluripotent stem cells under defined conditions revealed that neuronal progenitors, e.g. long-term self-renewing neuroepithelial-like stem cells, express the surface marker PSA-NCAM.³ Magnetically enriched, in vitro generated PSA-NCAM positive neural progenitors can be further differentiated into defined neuronal subtypes.


LS or autoMACS
  • Selected references

    1. Barral, S. et al. (2013)
      Efficient neuronal
      in vitro
      in vivo
      differentiation after immunomagnetic purification of mESC derived neuronal precursors.
      Stem Cell Res. 10(2): 133-46
Product options: 1
for 1×
total cells
USD 640.00