2nd MACS® Immuno-Oncology Day BeNeLux

T cell fitness and exhaustion

The 2nd annual MACS Immuno-Oncology Day BeNeLux returns. This time with a dedicated focus on T cells, and the numerous factors contributing to T cell fitness and exhaustion. Don’t miss your chance to take part in this event, fill in the form below to register. Attendance is free of charge.

January 31, 2020
9:00 a.m. to 6:00 p.m.
Salle Excelsior, Hotel Metropole Bruxelles, De Brouckère 31, 1000 Bruxelles

Did you know that this year we dedicate two travel awards of 500 euros each to Ph.D. researchers in the Benelux area? Please submit your abstract of max. 400 words before January 10, 2020 by email to Scientificday@miltenyibiotec.nl. The two selected winners will not only receive an award of 500 euros each, but will also have the opportunity to present their research at this event.

Details will be provided to the winners. 



09:00 a.m.Registration
09:15 a.m.Welcome 
Pierre van der Bruggen

Session 1: T cell fitness

09:25 a.m.How T cells fine-tune their response to infection and cancers 
Monika Wolkers, Sanquin Amsterdam, The Netherlands
10:00 a.m.Enhancing anti-tumour immunity with monoclonal antibodies; two ways with one receptor 
Sarah Buchan, University of Southampton, UK
10:35 a.m.Novel cosignaling molecules
Daniel Olive, Cancer Research Center of Marseille, France 
 Coffee break
11:30 a.m.Presentation IO travel award winner
11:45 a.m.Feeding your T cell army: metabolic barriers to effective cancer immunotherapy
Greg Delgoffe, University of Pittsburgh, USA

Session 2: Combination immunotherapy

12:20 p.m.Exploring the therapeutic potential of intratumoral myeloid dendritic cell therapy
Bart Neyns, Vrije Universiteit Brussel, Belgium
 Lunch break

Session 3: Metabolism and glycobiology

02:00 p.m.Glycans as key checkpoints of T cell activity and function
Salomé Pinho, University of Porto, Portugal 
02:35 p.m.Sialoadhesin/Siglec-1-dependent crosstalk between macrophages and regulatory T cells
Paul Crocker, University of Dundee, UK 

Session 4: T cell exhaustion

03:10 p.m.InTOXication causes T-cell exhaustion in chronic infection 
Dietmar Zehn, Technical University München, Germany
03:45 p.m.Presentation IO travel award winner
 Coffee break
04:20 p.m.NFAT, NR4A, and TOX transcription factors in 'exhaustion' of tumor-infiltrating lymphocytes
Patrick Hogan, La Jolla Institute for Immunology, USA 
04:55 p.m.Disturbed mitochondrial dynamics rewires epigenetic program for CD8+ TIL exhaustion
Ping-Chih Ho, University of Lausanne, Switzerland
05:40 p.m.Closing by Miltenyi Biotec