Simple exosome isolation and analysis

Already investigating exosomes or ready to explore these interceullular messengers that hold great promise for diagnostics and therapeutics? Either way, we have the right tools for you. Isolate highly pure exosomes directly from any source and simply screen multiple markers on exosomes at once by flow cytometry. Learn more about our research solutions for extracellular vesicles (EVs) like exosomes.

 

Magnetic isolation of highly pure exosomes

Magnetic isolation of extracellular vesicles

Accelerate exosome isolation with our easy to use Exosome Isolation Kits for human and mouse samples, a true alternative for conventional ultracentrifugation.

  • Selection of EVs according to surface markers i.e. CD9, CD63, CD81, or all three markers combined
  • Low starting volume of samples (0.5 to 2 mL)
  • Isolation from multiple sample types e.g. cell culture supernatant, urine, plasma, serum, ascites etc.
  • Complete workflow in <2 h
Western blot analysis of NK cell EVs and platelet EVs

Separation of EV subpopulations

MACS® technology enables the physical separation and enrichement of different EV subpoplations based on their surface markers. Exosomes isolated with our kits, are suitable for downstream molecular and genomic analysis.

 

Flow cytometric analysis of exosome surface markers

Flow cytometric analysis of exosome surface markers

Advance your exosome analysis with our MACSPlex Exosome Kits for human and mouse samples. Simply screen and profile multiple surface markers on EVs by flow cytometry in one go.

  • Unique multiplex bead platform for protein profiling of EVs by flow cytometry
  • Sensitive and semi-quantitative analysis of 37 markers in parallel (+ 2 isotype controls)
  • Fast (<2 h) and easy protocol
  • Works on any flow cytometer able to discriminate FITC, PE, and APC fluorescence
  • Direct detection possible; no pre-enrichment required
Surface marker profiles of extracellular vesicles isolated from plasma by ultracentrifugation or immunomagnetic isolation using the Exosome Isolation Kits CD9, CD63, or CD81.

Our kits make a difference

Plasma extracellular vesicles (EVs) isolated with our Exosome Isolation Kits* and analyzed with the MACSPlex Exosome Kit, human reveal strong signals in comparison to EVs isolated by ultracentrifugation.

Comprehensive exosome analysis by flow cytometry
 

Discover how some of our customers used our exosome research solutions to successfully investigate EVs