Available DNA dyes | |
Live cells | Hoechst 33342 Staining Solution, DRAQ5 Staining Solution |
Dead cells | Propidium Iodide Solution, 7-AAD Staining Solution, DAPI Staining Solution, CyTrak™ Orange Staining Solution |
Different proliferation- and cell cycle-related antigens have been described, allowing for the evaluation of cell kinetic parameters by detecting the expression of these antigens.
Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (CDK) enzymes. The most important cyclins involved in cell cycle processes are listed below.
Protein | Function | Inhibitory protein |
Cyclin A | Control of S phase in complex with Cdk1 or Cdk2 | Cdk1 or Cdk2 |
Cyclin B | Control of G2/M phase in complex with Cdk1 | Cdk1 |
Cyclin D | Control of G1 phase in complex with Cdk4 or Cdk6; Regulation of Rb/E2F transcription | Cdk4 or Cdk6 |
Cyclin E | Control of G1-S phase in complex with Cdk2; Regulation of Rb/E2F transcription | Cdk2 |
Cyclin H | Cdk-activating kinase and RNAPII transcription in complex with Cdk7 | Cdk7 |
Available products: