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As a global market leader with numerous subsidiaries and distributors, Miltenyi Biotec is committed to providing our customers around the world with the highest quality products. In addition to direct selling in more than 20 countries in North America, Europe and Asia/Pacific, Miltenyi Biotec also provides support for our customers through an extensive distributor network covering dozens of additional countries.
As a global market leader with numerous subsidiaries and distributors, Miltenyi Biotec is committed to providing our customers around the world with the highest quality products. In addition to direct selling in more than 20 countries in North America, Europe and Asia/Pacific, Miltenyi Biotec also provides support for our customers through an extensive distributor network covering dozens of additional countries.
MSCs have been investigated in a variety of clinical trials for the treatment of graft-versus-host disease and tissue regeneration. The antigen CD271 is expressed on MSCs and can be used for the magnetic enrichment of these cells. The characterization of CD271+ cells revealed that the colony-forming-unit fibroblast (CFU-F) potential is highly and exclusively enriched in the CD271+ cell fraction after enrichment using the CliniMACS® System. Following this strategy a well-defined cell population can be used either directly or expanded in culture for pre-clinical and clinical investigations. In addition, the cross-reactivity of the antibody shown in large animals may one day allow for an easy translation of pre-clinical investigations into the clinical area.
CliniMACS CD271 MicroBeads
CD271+ Mesenchymal Stromal Cells – CliniMACS CD271 Product line (reference list)
MSC-Brew GMP Medium is an optimized and standardized medium for the generation and expansion of MSCs from human bone marrow or other tissue sources. The formulation of MSC-Brew GMP Medium is designed to efficiently support the expansion of MSCs in vitro, while maintaining their differentiation potential. The medium is xeno- and serum-free and is manufactured under strictly controlled conditions using ingredients of the highest quality. MSC-Brew GMP Medium offers consistent lot-to-lot performance and optimal conditions for the cultivation of MSCs.
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