Why are MACS Columns designed for single use in manual separations, while autoMACS Columns can be used several times?

All MACS Columns are delivered sterile and individually packaged, enabling separation of cells under sterile conditions, a prerequisite for many downstream applications.

Using MACS Columns only one time for manual separations ensures optimal equilibration and column performance and avoids undesired contamination of cell samples.

autoMACS Columns can be used several times because once they are installed in the autoMACS Pro Separator, they remain permanently in liquid, preventing any oxygen-induced detrimental effects to the column matrix. In addition, autoMACS Columns undergo mandatory rinsing and cleaning after each separation using an appropriate washing program. When not in use, they are stored in 70% ethanol. autoMACS Columns can remain in the instrument for a maximum of two weeks.