Mouse IL-4 Secretion Assay – Detection Kit (PE)

Mouse IL-4 Secretion Assay – Detection Kit (PE)

The IL-4 Secretion Assay was developed for the sensitive detection of mouse IL-4-secreting cells.

Background information

Interleukin-4 (IL-4) is predominantly secreted by activated CD4
memory and effector T
2 cells, basophils, and mast cells. It induces and supports humoral immune responses for the neutralization of extracellular pathogens. The T
2 types of immune mechanisms can also be involved in immunologic disorders, such as IgE-mediated allergy.

Downstream applications

The assay has been used for research on T
2 development and commitment
and for evaluation of IL-4 regulation and expression
The Mouse IL-4 Secretion Assay (PE) is suitable for two-color cytokine analysis in combination with the Mouse IFN-γ, IL-2, IL-5, or IL-10 Secretion Assay - Detection Kit (APC).
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