IL-5 Secretion Assay – Detection Kit, human

IL-5 Secretion Assay – Detection Kit, human

The IL-5 Secretion Assay was developed for the sensitive detection of human IL-5-secreting cells.

Background information

Interleukin-5 (IL-5) is predominantly produced by CD4
+
T cells. IL-5 secretion has also been reported for γ/δ T cells, mast cells, NK cells, NKT cells, and eosinophils.
The cytokine was originally identified by its activity as a B cell growth factor and IgA-enhancing factor. Furthermore, IL-5 regulates growth, differentiation, activation, and survival of eosinophils from bone marrow into peripheral circulation (e.g. into lung following allergen exposure). It is involved in a range of allergic reactions and mediates immune reactions against parasites.
They can also be used for two-color cytokine analysis in combination with the IFN-γ, IL-2, IL-4, or IL-10 Secretion Assay - Detection Kits. The IL-5 Secretion Assay - Detection Kit (APC) can also be used for staining of IL-5-secreting cells in combination with peptide-MHC tetramers conjugated to R-phycoerythrin (PE).
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