IL-17 Secretion Assay – Detection Kits, human

IL-17 Secretion Assay – Detection Kits, human

The IL-17 Secretion Assay was developed for the detection of viable human IL-17–secreting leukocytes from PBMCs.

Background information

IL-17 is produced by CD4
T helper cells, a T cell subset termed Th17, which also secrete IL-17F and IL-22 and express the NK cell marker CD161
. IL-17 secretion has also been described for other cell types, such as CD8
memory T cells.
Th17 cells are involved in the recruitment of neutrophils to control early stages of infections by a number of pathogens, such as extracellular bacteria and fungi. IL-17 and Th17 cells play an important role in immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriasis, multiple sclerosis, asthma, and inflammatory bowel disease.
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