CD91 antibodies, human

CD91 antibodies, human

Clone: REA709 | Dilution: 1:50
Clone REA709 recognizes the human CD91 antigen, also known as low density lipoprotein receptor-related protein 1 (LRP1), alpha-2-macroglobulin receptor (A2MR), or apolipoprotein E receptor (APOER). CD91 is a type 1 transmembrane protein receptor protein which is located in the plasma membrane of cells involved in receptor-mediated endocytosis. Furthermore, CD91 plays a role in lipoprotein metabolism and cell motility, and different diseases, such as neurodegenerative diseases, atherosclerosis, and cancer. CD91 is mainly expressed in liver, brain, and lung.
Additional information: Clone REA709 displays negligible binding to Fc receptors.

Alternative Names

LRP-1, A2MR, APOER

Technical specifications

  • Antigen: CD91
  • Clone: REA709
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LRP-1, A2MR, APOER
  • Entrez Gene ID: 4035
  • Molecular mass of antigen [kDa]: 503
  • Distribution of antigen: liver, brain, lung cancer cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Herz, J. et al. (1988) Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7(13): 4119-4127
    2. Lillis, A.P. et al. (2005) Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability. J. Thromb. Haemost. 3(8): 1884-1993
    3. Etique, N. et al. (2013) LRP-1: a checkpoint for the extracellular matrix proteolysis. Biomed Res Int : 152-163
Product options: 12
130-111-416

CD91-VioBright FITC, human

for 30
tests
(1)
-
130-111-229

CD91-VioBright FITC, human

for 100
tests
(1)
-
130-111-412

CD91-PE, human

for 30
tests
(1)
-
130-111-225

CD91-PE, human

for 100
tests
(1)
-
130-111-413

CD91-APC, human

for 30
tests
(1)
-
130-111-226

CD91-APC, human

for 100
tests
(1)
-
130-111-414

CD91-PE-Vio770, human

for 30
tests
(1)
-
130-111-227

CD91-PE-Vio770, human

for 100
tests
(1)
-
130-111-415

CD91-PerCP-Vio700, human

for 30
tests
(1)
-
130-111-228

CD91-PerCP-Vio700, human

for 100
tests
(1)
-
130-111-411

CD91-Biotin, human

for 30
tests
(1)
-
130-111-224

CD91-Biotin, human

for 100
tests
(1)
-