CD9 antibodies, human

CD9 antibodies, human

Clone: SN4 C3-3A2 | Dilution: 1:11
Clone SN4 C3-3A2 recognizes the human CD9 antigen, a 24 kDa cell surface glycoprotein which is also known as tetraspanin-29 (Tspan-29). CD9 belongs to the tetraspanin family of integral proteins, which are characterised by the presence of four conserved transmembrane domains, a small and two large extracellular loops. Expression of CD9 is found on platelets, pre–B cells, fibroblasts, eosinophils, macrophages, basophils, epithelial cells, oocytes, and activated T cells. Further expression is reported on malignant cells and tumor cell lines where CD9 is involved in supressor functions, inhibition of cell invasion, and metastasis. CD9 associates with other tetraspanin members, cell adhesion molecules such as EpCAM, integrin subsets, transmembrane proteins (EWI-2 and EWI-F), choline receptors, and G-proteins. Through diverse interactions or via direct stimulation, CD9 influences various cellular functions including cell adhesion, aggregation, migration, clustering of MHC molecules in dendritic cells (DCs), and provides co-stimulatory signal during T cell activation.

Alternative Names

BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, Tspan29

Technical specifications

  • Antigen: CD9
  • Clone: SN4 C3-3A2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, Tspan29
  • Entrez Gene ID: 928
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: platelets, T cells, eosinophils, basophils, fibroblasts, macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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