CD8b antibodies, rat

CD8b antibodies, rat

Clone: REA222 | Dilution: 1:10
Clone REA222 recognizes rat CD8b, a member of the immunoglobulin superfamily also known as T cell surface glycoprotein Lyt-3. CD8b is expressed on cytotoxic T cells, thymocytes, and macrophages as a heterodimer with CD8a. CD8 identifies cytotoxic/suppressor T cells that interact with MHC class I bearing targets and plays a role in the process of T cell mediated killing. Flow cytometric analysis showed that CD8 T cells from lymph nodes or spleen of normal rats almost exclusively express the α/β heterodimer, regardless of the T cell receptor isotype. In contrast, natural killer cells carry only CD8a chains.
Additional information: Clone REA222 displays negligible binding to Fc receptors.

Alternative Names

Cd8b1

Technical specifications

  • Antigen: CD8b
  • Clone: REA222
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Cd8b1
  • Entrez Gene ID: 24931
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: NK cells, granulocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
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