CD8b.2 antibodies, mouse

CD8b.2 antibodies, mouse

Clone: REA865 | Dilution: 1:50
Clone REA865 recognizes the β chain of the mouse CD8 antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3.2 or Lyt-3.2). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8 αα homodimer or as a CD8 αβ heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8
+
lymphocyte subsets. The CD8 αβ heterodimer is expressed on cytotoxic T cells and thymocytes. CD8b functions as a co-receptor for the T cell receptor (TCR).
Additional information: Clone REA865 displays negligible binding to Fc receptors.

Alternative Names

Lyt-3.2, Ly-3.2

Technical specifications

  • Antigen: CD8b.2
  • Clone: REA865
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Lyt-3.2, Ly-3.2
  • Entrez Gene ID: 12526
  • Molecular mass of antigen [kDa]: 22
  • Distribution of antigen: T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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