CD8a antibodies, rat

CD8a antibodies, rat

Clone: REA437 | Dilution: 1:50
Clone REA437 recognizes the rat CD8a antigen, a single-pass type I membrane protein, which is also known as OX-8. CD8 acts as a co-receptor for the T cell receptor and recognizes antigen displayed by an antigen presenting cell in the context of class I MHC molecules. CD8a is expressed as a heterodimer with CD8b on T cell receptor (TCR) α/β and TCR γ/δ expressing, cytotoxic T cells, and on most thymocytes. As a homodimer of two CD8a chains the CD8 antigen is expressed on most NK cells, a major fraction of intestinal intraepithelial lymphocytes, some activated CD4
+
CD8
+
T cells and CD8
+
T cells from athymic rats. CD8a is also expressed by a T cell subset with regulatory functions.
Additional information: Clone REA437 displays negligible binding to Fc receptors.

Alternative Names

OX-8, Lyt2, Ly-2

Technical specifications

  • Antigen: CD8a
  • Clone: REA437
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: OX-8, Lyt2, Ly-2
  • Entrez Gene ID: 24930
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: NK cells, T cells, thymocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
Product options: 2

Product information

Size
Order no.
Price

CD8a-FITC, rat

  • REA437
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-119-664
-

CD8a-FITC, rat

  • REA437
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-119-564
-

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