CD87 antibodies, human

CD87 antibodies, human

Clone: REA892 | Dilution: 1:50
Clone REA892 recognizes the human CD87 antigen, a 36–38 kDa GPI-anchored cell-surface receptor. CD87, also known as uPAR, binds uPA and thus facilitating the catalytic C domain of the uPA to come in close proximity of membrane bound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in-turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. The expression of membrane-bound CD87 is found on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells, and keratinocytes. Multiple known regulatory functions of CD87 include cell migration, leukocyte adhesion, chemotaxis, signal transduction, and tissue remodeling.
Additional information: Clone REA892 displays negligible binding to Fc receptors.

Alternative Names

PLAUR, U-PAR, URKR, uPAR, MO3

Technical specifications

  • Antigen: CD87
  • Clone: REA892
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PLAUR, U-PAR, URKR, uPAR, MO3
  • Entrez Gene ID: 5329
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: granulocytes, monocytes, macrophages, dendritic cells, fibroblasts, endothelial cells, keratinocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD87-FITC, human

  • REA892
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-891
-

CD87-FITC, human

  • REA892
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-849
-

CD87-PE, human

  • REA892
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-892
-

CD87-PE, human

  • REA892
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-850
-

CD87-APC, human

  • REA892
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-893
-

CD87-APC, human

  • REA892
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-851
-

CD87-PE-Vio615, human

  • REA892
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-895
-

CD87-PE-Vio615, human

  • REA892
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-853
-

CD87-Biotin, human

  • REA892
  • 1:50
  • For research use only
for 30
tests
(1)
130-114-890
-

CD87-Biotin, human

  • REA892
  • 1:50
  • For research use only
for 100
tests
(1)
130-114-848
-

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