CD86 antibodies, human

CD86 antibodies, human

Clone: FM95 | Dilution: 1:11
CD86, also known as B7-2 or B70, is an 80 kDa molecule and a member of the immunoglobulin superfamily. Together with CD80 (B7-1) it belongs to the B7 family of co-stimulatory molecules. CD86 is expressed on activated B and T cells, dendritic cells, and monocytes/macrophages. The interaction of CD86 with its ligands CD28 and CD152 (CTLA- 4) plays a critical role in induction and regulation of immune responses, e.g., cross-talk between T and B cells, T cell co-stimulation, or immunoglobulin class-switching. Binding of CD86 to CD28 on T cells results in transduction of co-stimulatory signals for activation or proliferation of T cells, or cytokine production.

Alternative Names

B7-2, B70, CD28LG2, LAB72

Technical specifications

  • Antigen: CD86
  • Clone: FM95
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: B7-2, B70, CD28LG2, LAB72
  • Entrez Gene ID: 942
  • Molecular mass of antigen [kDa]: 35
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, Langerhans cells, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, VioBlue, PE-Vio770, PerCP-Vio700, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD86-FITC, human

  • FM95
  • 1:11
  • For research use only
for 30
tests
(1)
130-098-182
-

CD86-FITC, human

  • FM95
  • 1:11
  • For research use only
for 100
tests
(1)
130-094-878
-

CD86-PE, human

  • FM95
  • 1:11
  • For research use only
for 30
tests
(1)
130-098-198
-

CD86-PE, human

  • FM95
  • 1:11
  • For research use only
for 100
tests
(1)
130-094-877
-

CD86-VioBlue, human

  • FM95
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-101
-

CD86-VioBlue, human

  • FM95
  • 1:11
  • For research use only
for 100
tests
(1)
130-100-100
-

CD86-PE-Vio770, human

  • FM95
  • 1:11
  • For research use only
for 100
tests
(1)
130-098-214
-

CD86-PerCP-Vio700, human

  • FM95
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-918
-

CD86-Biotin, human

  • FM95
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-178
-

CD86-Biotin, human

  • FM95
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-177
-

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