CD83 antibodies, mouse

CD83 antibodies, mouse

Clone: REA304 | Dilution: 1:10
Clone REA304 recognizes the mouse CD83 antigen, a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily. Murine CD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic peptides or T cell receptor-specific monoclonal antibody. When returning to the resting state, T cells down-regulate CD83 again. Histological analysis of serial spleen sections revealed a CD83 expression pattern resembling that of MIDC-8, a known murine DC marker molecule.
Additional information: Clone REA304 displays negligible binding to Fc receptors.

Alternative Names

B-cell activation protein, Cell surface protein HB15

Technical specifications

  • Antigen: CD83
  • Clone: REA304
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: B-cell activation protein, Cell surface protein HB15
  • Entrez Gene ID: 12522
  • Molecular mass of antigen [kDa]: 19
  • Distribution of antigen: T cells, dendritic cells, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
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