CD81 antibodies, mouse and rat

CD81 antibodies, mouse and rat

Clone: EAT2 | Dilution: 1:10
CD81 is widely expressed and is involved in a variety of biological processes. In the brain it is expressed on astrocytes, oligodendrocytes, microglia, and endothelial cells. The CD81 antigen is a 26 kDa cell surface glycoprotein, also known as TAPA-1, and a member of the tetraspanin family, characterised by the presence of four hydrophobic domains. CD81 is known to complex with integrins, and mediates signal transduction events in the regulation of muscle cell fusion, myotube maintenance, signal transduction, cell development, activation, growth, and motility. The CD81 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.

Alternative names

CVID6, S5.7, TAPA1, TSPAN28

Technical specifications

  • Antigen: CD81
  • Clone: EAT2
  • Isotype: hamster IgGκ
  • Alternative names of antigen: CVID6, S5.7, TAPA1, TSPAN28
  • Entrez Gene ID: 12520
  • Molecular mass of antigen [kDa]: 26
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, endothelial cells, epithelial cells, granulocytes, leukocytes, lymphocytes, monocytes, ES and iPS cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, VioGreen, Biotin
  • Selected references

    1. Kelic, L. et al. (2011) CD81 regulates neuron-induced astrocyte cell-cycle exit. Mol. Cell. Neurosci. 17: 551-560
    2. Levy, S. et al. (1998) CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu. Rev. Immunol. 16: 89-109
Product options: 8
130-102-631

CD81-FITC, mouse and rat

30 µg in 1 mL (1)
-
130-102-632

CD81-PE, mouse and rat

30 µg in 1 mL (1)
-
130-102-630

CD81-APC, mouse and rat

30 µg in 1 mL (1)
-
130-103-144

CD81-VioBlue, mouse and rat

9 µg in 300 µL (1)
-
130-102-633

CD81-VioBlue, mouse and rat

30 µg in 1 mL (1)
-
130-108-390

CD81-VioGreen, mouse and rat

9 µg in 300 µL (1)
-
130-108-361

CD81-VioGreen, mouse and rat

30 µg in 1 mL (1)
-
130-101-966

CD81-Biotin, mouse and rat

30 µg in 1 mL (1)
-