CD81 antibodies, human

CD81 antibodies, human

Clone: REA513 | Dilution: 1:11
Clone REA513 recognizes the human CD81 antigen, a multi-pass membrane protein also known as TAPA-1. It is a member of the tetraspanin family including, for example, CD9, CD37, CD53, CD63, CD82, and CD151. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. The 26 kDa cell surface protein is involved in adhesion, activation, proliferation, and differentiation of B cells, T cells, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. Similarly on T cells CD81 associates with CD4 and CD8 and provides a costimulatory signal with CD3. CD81 is expressed by epithelial and endothelial cells, T and B cells, as well as NK cells.
Additional information: Clone REA513 displays negligible binding to Fc receptors.

Alternative Names

CVID6, S5.7, TAPA1, TSPAN28

Technical specifications

  • Antigen: CD81
  • Clone: REA513
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CVID6, S5.7, TAPA1, TSPAN28
  • Entrez Gene ID: 975
  • Molecular mass of antigen [kDa]: 26
  • Cross-reactivity:
    chimpanzee (
    Pan troglodytes
    )
  • Distribution of antigen: epithelial cells, endothelial cells, T cells, B cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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