CD72 antibodies, human

CD72 antibodies, human

Clone: REA231 | Dilution: 1:11
Clone REA231 recognizes CD72, a 45 kDa type II membrane protein with a C-type lectin-like domain. Expression of CD72 is found on most B-lineage cells, follicular dendritic cells, mast cells, and liver Kupffer cells. CD72 is recognized as negative regulator of B cell receptor (BCR) signaling, as well as regulating mast cell growth and differentiation via KIT activation. The inhibitory role of CD72 is exerted via the ITIM sequence in the cytoplasmic tail.
Additional information: Clone REA231 displays negligible binding to Fc receptors.

Alternative names

CD72b, Lyb-2

Technical specifications

  • Antigen: CD72
  • Clone: REA231
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD72b, Lyb-2
  • Distribution of antigen: B cells, mast cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Kataoka, T. R. et al. (2010) CD72 negatively regulates KIT-mediated responses in human mast cells. J. Immunol. 184: 2468-2475
    2. Li, D. H. et al. (2006) CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. J. Immunol. 176: 5321-5328
Product options: 14
130-101-340

CD72-FITC, human

for 30
tests
(1)
-
130-101-338

CD72-FITC, human

for 100
tests
(1)
-
130-101-336

CD72-PE, human

for 30
tests
(1)
-
130-101-335

CD72-PE, human

for 100
tests
(1)
-
130-101-334

CD72-APC, human

for 30
tests
(1)
-
130-101-333

CD72-APC, human

for 100
tests
(1)
-
130-106-502

CD72-VioBlue, human

for 30
tests
(1)
-
130-106-454

CD72-VioBlue, human

for 100
tests
(1)
-
130-101-330

CD72-PE-Vio770, human

for 30
tests
(1)
-
130-101-327

CD72-PE-Vio770, human

for 100
tests
(1)
-
130-101-325

CD72-APC-Vio770, human

for 30
tests
(1)
-
130-101-321

CD72-APC-Vio770, human

for 100
tests
(1)
-
130-101-332

CD72-Biotin, human

for 30
tests
(1)
-
130-101-331

CD72-Biotin, human

for 100
tests
(1)
-