CD7 antibodies, human

CD7 antibodies, human

Clone: CD7-6B7 | Dilution: 1:11
Clone CD7-6B7 recognizes the human CD7 antigen, a single-pass type I membrane protein, also known as leu-9 or GP40. CD7 appears early in T cell ontogeny and is expressed by most T cells in the periphery. It is also found on NK cells, hematopoietic progenitors, monocytes, acute lymphocytic leukemia, and some acute myeloid leukemia cells. Although the ligand is yet not identified, CD7 has been recognized as a co-stimulatory molecule. CD7 activates phosphatidylinositol 3-kinase which is involved in CD7-mediated regulation of integrin adhesiveness. Furthermore, it has been reported that the β-galactoside-binding lectin galectin-1 binds CD7, leading to induction of apoptosis of thymocytes and T cells, with implications for certain autoimmune diseases and T cell lymphomas.

Alternative Names

GP40, Leu-9, TP41, Tp40

Technical specifications

  • Antigen: CD7
  • Clone: CD7-6B7
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: GP40, Leu-9, TP41, Tp40
  • Entrez Gene ID: 924
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: T cells, NK cells, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
Product options: 14

Product information

Size
Order no.
Price

CD7-VioBright FITC, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-903
-

CD7-VioBright FITC, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-844
-

CD7-PE, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-899
-

CD7-PE, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-840
-

CD7-APC, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-900
-

CD7-APC, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-841
-

CD7-VioBlue, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-508
-

CD7-VioBlue, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-459
-

CD7-PE-Vio770, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-901
-

CD7-PE-Vio770, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-842
-

CD7-APC-Vio770, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-902
-

CD7-APC-Vio770, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-843
-

CD7-Biotin, human

  • CD7-6B7
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-898
-

CD7-Biotin, human

  • CD7-6B7
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-839
-

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