CD68 antibodies, rat

CD68 antibodies, rat

Clone: REA237 | Dilution: 1:10
Clone REA237 recognizes rat CD68, also known as macrosialin, which is a heavily glycosylated type I transmembrane protein of the LAMP (lysosomal-associated membrane protein) family. CD68 is expressed by the majority of tissue macrophages and weakly by peripheral blood granulocytes. It is also present on rat Kupffer cells but absent from rat liver endothelial cells. The expression of rat CD68 is predominantly intracellular, but it is reported that weak cell surface expression also occurs as well. CD68 functions as a macrophage receptor for oxidized low density lipoprotein.
Additional information: Clone REA237 displays negligible binding to Fc receptors.

Technical specifications

  • Antigen: CD68
  • Clone: REA237
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Entrez Gene ID: 287435
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: macrophages, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770
  • Selected References

    1. Rabinowitz, S. S. et al. (1991) Macrosialin, a macrophage-restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli. J. Exp. Med. 174(4): 827-836
    2. Van Velzen, A. G. et al. (1997) Characterization of a receptor for oxidized low-density lipoproteins on rat Kupffer cells: similarity to macrosialin. Biochem. J. 1(322): 411-415
Product options: 10
130-103-362

CD68-FITC, rat

9 µg in 300 µL (1)
-
130-102-723

CD68-FITC, rat

30 µg in 1 mL (1)
-
130-103-363

CD68-PE, rat

9 µg in 300 µL (1)
-
130-102-724

CD68-PE, rat

30 µg in 1 mL (1)
-
130-103-364

CD68-APC, rat

9 µg in 300 µL (1)
-
130-102-725

CD68-APC, rat

30 µg in 1 mL (1)
-
130-103-365

CD68-PE-Vio770, rat

9 µg in 300 µL (1)
-
130-102-726

CD68-PE-Vio770, rat

30 µg in 1 mL (1)
-
130-103-366

CD68-APC-Vio770, rat

9 µg in 300 µL (1)
-
130-102-727

CD68-APC-Vio770, rat

30 µg in 1 mL (1)
-