CD66a antibodies, mouse

CD66a antibodies, mouse

Clone: REA410 | Dilution: 1:10
Clone REA410 recognizes the mouse CD66a antigen, a Single-pass type I membrane protein which is also known as Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1). CD66a is an adhesion molecule that is involved in many immune responses associated with infection, inflammation and cancer. In the mouse, CD66a is expressed on the plasma membranes of a variety of cells and tissues like endothelial cells, macrophages, dendritic cells, thymic epithelial cells, B lymphocytes and activated T lymphocytes. CD66a is also the principal receptor for mouse hepatitis virus (MHV). Wild mice have two alleles of the mCeacam1 gene, called mCeacam1a and mCeacam1b. Inbred mouse strains that are homozygous for the isoform Ceacam1a, including BALB/c, C57BL/6 (B6), C3H, and A/J mice, are highly susceptible to infection with strains of MHV. In contrast, the SJL line of inbred mice, which is resistant to death from MHV infection, is homozygous for the Ceacam1b isoform, which is not recognized by clone REA410.
Additional information: Clone REA410 displays negligible binding to Fc receptors.

Alternative Names

Ceacam1, BGP, BGP-1, MHV-R, MHVR1, Bgpd, CEACAM1

Technical specifications

  • Antigen: CD66a
  • Clone: REA410
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Ceacam1, BGP, BGP-1, MHV-R, MHVR1, Bgpd, CEACAM1
  • Entrez Gene ID: 26365
  • Molecular mass of antigen [kDa]: 54
  • Distribution of antigen: endothelial cells, macrophages, dendritic cells, epithelial cells, lymphocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
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