CD64 antibodies, human

CD64 antibodies, human

Clone: 10.1.1
Clone 10.1.1 reacts with human CD64, a high affinity Fc receptor for IgG. CD64 contains three Ig-like domains in its extracellular domain and binds both monomeric and aggregated IgG and contributes to antibody-dependent cellular cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. It is constitutively expressed on macrophages, monocytes, and eosinophils and can be up-regulated on neutrophils during infection or after stimulation with IFN-γ and colony-stimulating factors G-CSF and GM-CSF.

Alternative Names

FCGR1A, CD64A, FcR I, IGFR1, FcγRI

Technical specifications

  • Antigen: CD64
  • Clone: 10.1.1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: FCGR1A, CD64A, FcR I, IGFR1, FcγRI
  • Entrez Gene ID: 2209
  • Molecular mass of antigen [kDa]: 41
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon, capuchin monkey,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: dendritic cells, eosinophils, macrophages, monocytes, myeloid cells, neutrophils
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD64 pure, human

  • 10.1.1
  • For research use only
100 µg in 100 µL
130-108-046
-