CD63 antibodies, human

CD63 antibodies, human

Clone: REA1055 | Dilution: 1:50
Clone REA1055 recognizes the human CD63 antigen, a type III glycoprotein belonging to the tetraspanin family of proteins, which are characterized by four membrane spanning domains. Tetraspanins via various homotypic and heterotypic interactions regulate the spatial location and trafficking of associated transmembrane partners, eventually regulating and co-ordinating various signaling pathways. CD63, like other tetraspanins, is present in the plasma membrane and membrane of various subcellular compartments such as late endosomes, lysososmes, cytotoxic granules of T lymphocytes, the crystalloid granules of eosinophils, the secretory granules of basophils, and mast cells. Interaction partners of CD63 include MHC class II molecules in immature dendritic cells and B lymphocytes, FcεRI in basophils and mast cells, etc.
Additional information: Clone REA1055 displays negligible binding to Fc receptors.

Alternative Names

LAMP-3, ME491, MLA1, OMA81H, Tspan30, LIMP1

Technical specifications

  • Antigen: CD63
  • Clone: REA1055
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LAMP-3, ME491, MLA1, OMA81H, Tspan30, LIMP1
  • Entrez Gene ID: 967
  • Molecular mass of antigen [kDa]: 26
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: B cells, eosinophils, granulocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770
Product options: 8
130-118-149

CD63-FITC, human

for 30
tests
(1)
-
130-118-076

CD63-FITC, human

for 100
tests
(1)
-
130-118-150

CD63-PE, human

for 30
tests
(1)
-
130-118-077

CD63-PE, human

for 100
tests
(1)
-
130-118-151

CD63-APC, human

for 30
tests
(1)
-
130-118-078

CD63-APC, human

for 100
tests
(1)
-
130-118-154

CD63-PE-Vio770, human

for 30
tests
(1)
-
130-118-081

CD63-PE-Vio770, human

for 100
tests
(1)
-