CD61 antibodies, human

CD61 antibodies, human

Clone: REA761 | Dilution: 1:50
Clone REA761 recognizes the human CD61 antigen, a cell surface protein belonging to the integrin family. CD61 is also known as the integrin β3-subunit. It associates with CD41 to form the heterodimeric gpIIb/gpIIIa complex that is present on human megakaryocytes and platelets and mediates cell adhesion processes. Together with CD51, CD61 forms the vitronectin receptor, which is present on platelets as well as on a variety of other cell types such as osteoclasts and endothelial vessel cells. Clone REA761 specifically recognizes the integrin β3-chain of both heterodimeric complexes.
Additional information: Clone REA761 displays negligible binding to Fc receptors.

Alternative Names

ITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT

Technical specifications

  • Antigen: CD61
  • Clone: REA761
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT
  • Entrez Gene ID: 3690
  • Molecular mass of antigen [kDa]: 84
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: B cells, CNS cells, endothelial cells, fibroblasts, macrophages, mast cells, megakaryocytes, monocytes, plasma cells, smooth muscle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Naik, U. P. et al. (1997) Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain. J. Biol. Chem. 272(8): 4651-4654
    2. Kumar, C. S. et al. (1997) Cloning and characterization of a novel integrin beta3 subunit. J. Biol. Chem. 272(26): 16390-16397
    3. Hynes, R. O. (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110(6): 673-687
Product options: 22
130-110-885

CD61-FITC, human

for 30
tests
(1)
-
130-110-748

CD61-FITC, human

for 100
tests
(1)
-
130-110-886

CD61-PE, human

for 30
tests
(1)
-
130-110-749

CD61-PE, human

for 100
tests
(1)
-
130-110-887

CD61-APC, human

for 30
tests
(1)
-
130-110-750

CD61-APC, human

for 100
tests
(1)
-
130-110-891

CD61-VioBlue, human

for 30
tests
(1)
-
130-110-754

CD61-VioBlue, human

for 100
tests
(1)
-
130-110-892

CD61-VioGreen, human

for 30
tests
(1)
-
130-110-755

CD61-VioGreen, human

for 100
tests
(1)
-
130-110-893

CD61-PE-Vio615, human

for 30
tests
(1)
-
130-110-756

CD61-PE-Vio615, human

for 100
tests
(1)
-
130-110-888

CD61-PE-Vio770, human

for 30
tests
(1)
-
130-110-751

CD61-PE-Vio770, human

for 100
tests
(1)
-
130-110-889

CD61-APC-Vio770, human

for 30
tests
(1)
-
130-110-752

CD61-APC-Vio770, human

for 100
tests
(1)
-
130-110-890

CD61-PerCP-Vio700, human

for 30
tests
(1)
-
130-110-753

CD61-PerCP-Vio700, human

for 100
tests
(1)
-
130-110-894

CD61-VioBright 515, human

for 30
tests
(1)
-
130-110-757

CD61-VioBright 515, human

for 100
tests
(1)
-
130-110-884

CD61-Biotin, human

for 30
tests
(1)
-
130-110-747

CD61-Biotin, human

for 100
tests
(1)
-