CD56 antibodies, human

CD56 antibodies, human

Clone: REA196 | Dilution: 1:11
Clone REA196 recognizes the human CD56 antigen, a glycoprotein of the Ig-superfamily, also known as neural cell adhesion molecule (NCAM), which is expressed in blood on practically all resting and activated NK cells and on a minor subset of CD3
+
T cells. CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal-derived tumors, myelomas, and myeloid leukemias also express CD56.
Additional information: Clone REA196 displays negligible binding to Fc receptors.

Alternative Names

NCAM1, MSK39, NCAM

Technical specifications

  • Antigen: CD56
  • Clone: REA196
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: NCAM1, MSK39, NCAM
  • Entrez Gene ID: 4684
  • Molecular mass of antigen [kDa]: 92
  • Cross-reactivity:
    chimpanzee (
    Pan troglodytes
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE-Vio615, PerCP-Vio700, VioBright 667
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clones Overlap in epitope recognition with REA196
NCAM16.2 ++
TULY56 ++
5.1H11 ++
AF12-7H3 -
C5.9 ++
N901/NKH1 ++
CMSSB +
B159

 -

HCD56-
MEM188-
Product options: 5

Product information

Size
Order no.
Price

CD56-PE-Vio615, human

  • REA196
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-193
-

CD56-PerCP-Vio700, human

  • REA196
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-679
-

CD56-PerCP-Vio700, human

  • REA196
  • 1:11
  • For research use only
for 100
tests
(1)
130-100-681
-

CD56-VioBright 667, human

  • REA196
  • 1:11
  • For research use only
for 30
tests
(1)
130-111-926
-

CD56-VioBright 667, human

  • REA196
  • 1:11
  • For research use only
for 100
tests
(1)
130-111-755
-

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