CD51/CD61 antibodies, human

CD51/CD61 antibodies, human

Clone: REA1099 | Dilution: 1:50
Clone REA1099 recognizes the human heterodimeric complex CD51/CD61, also known as integrin αv/β3. The dimers are expressed on melanoma cells, endothelial cells, on osteoclasts, and in a very low density on platelets. The CD51/CD61 complex mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, osteopontin, and collagen.
Additional information: Clone REA1099 displays negligible binding to Fc receptors.

Alternative names

ITGAV, MSK8, VNRA, VTNR, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3

Technical specifications

  • Antigen: CD51/CD61
  • Clone: REA1099
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGAV, MSK8, VNRA, VTNR, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3
  • Entrez Gene ID: 3685, 3690
  • Molecular mass of antigen [kDa]: 197
  • Cross-reactivity: rabbit, chicken
  • Distribution of antigen: endothelial cells, melanoma, osteoclasts, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, VioBright 515
  • Selected references

    1. Athanasou, N. A. et al. (1990) New sites of cellular vitronectin receptor immunoreactivity detected with osteoclast-reacting monoclonal antibodies 13C2 and 23C6. Bone Marrow Transplant. 8(1): 7-22
    2. Chuntharapai, A. et al. (1993) Blocking monoclonal antibodies to alpha V beta 3 integrin: a unique epitope of alpha V beta 3 integrin is present on human osteoclasts. Exp. Cell Res. 205(2): 345-352
Product options: 8
130-119-229

CD51/CD61-PE, human

for 30
tests
(1)
-
130-119-052

CD51/CD61-PE, human

for 100
tests
(1)
-
130-119-230

CD51/CD61-APC, human

for 30
tests
(1)
-
130-119-053

CD51/CD61-APC, human

for 100
tests
(1)
-
130-119-232

CD51/CD61-PE-Vio770, human

for 30
tests
(1)
-
130-119-055

CD51/CD61-PE-Vio770, human

for 100
tests
(1)
-
130-119-235

CD51/CD61-VioBright 515, human

for 30
tests
(1)
-
130-119-058

CD51/CD61-VioBright 515, human

for 100
tests
(1)
-