CD49e antibodies, mouse

CD49e antibodies, mouse

Clone: 5H10-27 | Dilution: 1:10
The monoclonal antibody 5H10-27 recognizes mouse CD49e, also known as integrin α5, which interacts with integrin β1 (CD29) to form the heterodimer VLA-5, the fibronectin receptor. It is expressed on activated T cells, thymocytes, mast cells, and splenic B cells and plays a role in cell-surface mediated signaling and in adhesion. The 5H10-27 antibody has been shown to inhibit VLA-5 mediated functions and promote the stimulation of CD8
+
cells
in vitro
.

Alternative Names

ITGA5, FNRA, VLA5

Technical specifications

  • Antigen: CD49e
  • Clone: 5H10-27
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: ITGA5, FNRA, VLA5
  • Entrez Gene ID: 16402
  • Molecular mass of antigen [kDa]: 110
  • Distribution of antigen: T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
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