CD49d antibodies, rat

CD49d antibodies, rat

Clone: MRα4-1 | Dilution: 1:50
Clone MRα4-1 recognizes the mouse CD49d antigen, a 150 kDa integrin family member, also known as integrin α4 chain or VLA-4α chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD49d associates non-covalently with the integrin ß or ß1 (CD29) forming the complex VLA-4, which is expressed on peripheral lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, and monocytes. VLA-4 plays a critical role in adhesion and migration of cells into tissues by binding to its ligand VCAM-1 (CD106). In T cells, on ligation of MAdCAM-1, α4β7 integrin also provides costimulation of T cell receptor/CD3–mediated signaling.

Alternative Names

ITGA4, α4 integrin chain, VLA-4α chain

Technical specifications

  • Antigen: CD49d
  • Clone: MRα4-1
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: ITGA4, α4 integrin chain, VLA-4α chain
  • Entrez Gene ID: 311144
  • Molecular mass of antigen [kDa]: 116
  • Distribution of antigen: lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD49d-VioBright FITC, rat

  • MRα4-1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-487
-

CD49d-VioBright FITC, rat

  • MRα4-1
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-301
-

CD49d-PE, rat

  • MRα4-1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-483
-

CD49d-PE, rat

  • MRα4-1
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-297
-

CD49d-APC, rat

  • MRα4-1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-484
-

CD49d-APC, rat

  • MRα4-1
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-298
-

CD49d-PE-Vio770, rat

  • MRα4-1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-485
-

CD49d-PE-Vio770, rat

  • MRα4-1
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-299
-

CD49d-Biotin, rat

  • MRα4-1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-482
-

CD49d-Biotin, rat

  • MRα4-1
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-296
-

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