CD49b antibodies, human

CD49b antibodies, human

Clone: REA188 | Dilution: 1:11
Clone REA188 recognizes CD49b, also known as integrin α2 chain. CD49b is single-pass, 150 KDa, type I membrane protein. Together with integrin β1 (CD29), CD49b forms the VLA-2 receptor, which binds ligands such as collagen, fibrinogen, and laminin and thus mediate the attachment of several cell types to extracellular matrix. Expression of CD49b is found on lymphocytes, activated T cells, monocytes, epithelial cells, and platelets.
Additional information: Clone REA188 displays negligible binding to Fc receptors.

Alternative Names

Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α

Technical specifications

  • Antigen: CD49b
  • Clone: REA188
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α
  • Entrez Gene ID: 3673
  • Molecular mass of antigen [kDa]: 126
  • Distribution of antigen: monocytes, platelets, megakaryocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
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