CD45RA antibodies, human

CD45RA antibodies, human

Clone: REA562 | Dilution: 1:11
Clone REA562 recognizes the human CD45RA antigen, which is expressed on naive CD4
+
and CD8
+
T cells as well as on CD8
+
effector T cells. CD45RA is also present on subsets of B and NK cells as well as on plasmacytoid dendritic cells. The CD45RA antibody recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase.
Additional information: Clone REA562 displays negligible binding to Fc receptors

Alternative Names

Ptprc, B220, CD45R, GP180, L-CA, LY5, T200
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the different hybridoma clones. 
Other clonesOverlap in epitope recognition with REA562
HI100-
L48++
JS-83++
T6D11++
REA1047-

Technical specifications

  • Antigen: CD45RA
  • Clone: REA562
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, B220, CD45R, GP180, L-CA, LY5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: T cells, B cells, NK cells, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioGreen, PE-Vio615, PerCP-Vio700
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