CD44H antibodies, rat

CD44H antibodies, rat

Clone: REA505 | Dilution: 1:10
Clone REA505 recognizes the rat CD44H antigen, a transmembrane glycoprotein, also known as homing-associated cell adhesion molecule (H-CAM) or phagocytic glycoprotein-1 (Pgp-1). CD44H belongs to the CD44 group, that encompasses several isoforms expressed in a variety of tissues. It is highly expressed on hematopoietic and non-hematopoietic cells. All isoforms are encoded by the same gene on chromosome 11 and are formed by alternative splicing of their mRNA. CD44 isoforms belong to the family of cell adhesion molecules and to the sub-family of the hyaladherins in consideration of their affinity for hyaluronate and their structural homology with the cartilage link protein. The standard form of CD44, CD44H, exhibits a high affinity for hyaluronate, plays a role in the uptake and degradation of this glycosaminoglycan, and participates in cell locomotion in its presence.
Additional information: Clone REA505 displays negligible binding to Fc receptors.

Alternative Names

CD44s, CD44A, METAA, RHAMM, CD44, Pgp-1, H-CAM, CD44st, CD44std

Technical specifications

  • Antigen: CD44H
  • Clone: REA505
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CD44s, CD44A, METAA, RHAMM, CD44, Pgp-1, H-CAM, CD44st, CD44std
  • Entrez Gene ID: 25406
  • Molecular mass of antigen [kDa]: 54
  • Distribution of antigen: hematopoietic cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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