CD40 antibodies, mouse

CD40 antibodies, mouse

Clone: REA965 | Dilution: 1:50
Clone REA965 recognizes the mouse CD40 antigen, a 40–50 kDa glycoprotein and member of the tumor necrosis factor receptor (TNFR) family. CD40 is expressed on B lymphocytes, macrophages, and dendritic cells. It is an important costimulatory molecule for B cells as well as dendritic cells, monocytes, and other antigen-presenting cells (APCs). The interaction of CD40 on B cells with its ligand CD154 is involved in B cell activation and differentiation; engagement of CD40 on dendritic cells leads to maturation.
Additional information: Clone REA965 displays negligible binding to Fc receptors.

Alternative Names

Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50

Technical specifications

  • Antigen: CD40
  • Clone: REA965
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50
  • Entrez Gene ID: 21939
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, epithelial cells, fibroblasts, lymphocytes, macrophages, mast cells, monocytes, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515

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