CD40 antibodies, mouse

CD40 antibodies, mouse

Clone: FGK45.5 | Dilution: 1:10
Clone FGK45.5 recognizes the mouse CD40 antigen, a 40–50 kDa glycoprotein and member of the tumor necrosis factor receptor (TNFR) family. CD40 is expressed on B lymphocytes, macrophages, and dendritic cells. It is an important costimulatory molecule for B cells as well as dendritic cells, monocytes, and other antigen-presenting cells (APCs). The interaction of CD40 on B cells with its ligand CD154 is involved in B cell activation and differentiation; engagement of CD40 on dendritic cells leads to maturation.
Clone FGK45 can be used for blocking of CD40/CD154 interaction and for
in vitro
in vivo
activation of CD40 expressing APCs.

Alternative Names

Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50

Technical specifications

  • Antigen: CD40
  • Clone: FGK45.5
  • Isotype: rat IgG2a
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50
  • Entrez Gene ID: 21939
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, epithelial cells, fibroblasts, Langerhans cells, leukemia cells, lymphocytes, macrophages, mast cells, monocytes, plasma cells, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, VioBright FITC, PE, APC, PE-Vio770, Biotin
Product options: -

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