CD4 antibodies, human

CD4 antibodies, human

Clone: M-T466 | Dilution: 1:11
CD4 is a type I transmembrane glycoprotein involved in the recognition of MHC class II/peptide complexes by the TCR heterodimers. CD4 is highly expressed on T helper cells and at a lower level on monocytes and dendritic cells. The CD4 molecule is the receptor for the human immunodeficiency virus. The CD4 antibody recognizes the human CD4 antigen which is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. It is responsible for the recognition of the MHC class II antigen.

Alternative Names

CD4mut, L3T4, Leu-3, T4

Cross-reactivity

This antibody is tested to cross-react with T helper cells from
  • Rhesus monkey (Macaca mulatta)
  • Cynomolgus monkey (Macaca fascicularis)

Technical specifications

  • Antigen: CD4
  • Clone: M-T466
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CD4mut, L3T4, Leu-3, T4
  • Entrez Gene ID: 920
  • Molecular mass of antigen [kDa]: 48
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: dendritic cells, granulocytes, Langerhans cells, lymphocytes, macrophages, monocytes, neutrophils, T cells, T helper cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: With the exception of the FITC conjugate the antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC-Vio770, PerCP-Vio700, Biotin
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