CD3ε antibodies, mouse

CD3ε antibodies, mouse

Clone: REA606 | Dilution: 1:10
Clone REA606 recognizes the mouse CD3ε antigen, a single-pass type I membrane protein, which is a part of the CD3 complex and a subunit of the TCR complex. The CD3 complex mediates signal transduction in several intracellular pathways and has a role in T cell activation and antigen recognition by binding the peptide/MHC antigen complex. CD3ε is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes.
Additional information: Clone REA606 displays negligible binding to Fc receptors.

Alternative Names

CD3e, CD3epsilon, CD3, T3

Technical specifications

  • Antigen: CD3ε
  • Clone: REA606
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CD3e, CD3epsilon, CD3, T3
  • Entrez Gene ID: 12501
  • Molecular mass of antigen [kDa]: 19
  • Distribution of antigen: T cells, NKT cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, PE-Vio615, PE-Vio770
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA606
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