CD36L1 (SR-BI) antibodies, human

CD36L1 (SR-BI) antibodies, human

Clone: REA716 | Dilution: 1:50
Clone REA716 recognizes the human CD36L1 antigen, an integral membrane protein, also known as SR-BI. CD36L1 is widly expressed, e.g. on macrophages, dendritic cells, adrenocortical cells, adipocytes, and trophoblastic cells. In hepatocytes, CD36L1 acts as a receptor for hepatitis C. It has been reported, that CD36L1 is able to bind HCV envelope glycoprotein E2, participate in entry of HCV pseudotype particles, and modulate HCV infection. Furthermore, CD36L1 is a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, vitamin E, phosphatidylserine, and apoptotic cells.
Additional information: Clone REA716 displays negligible binding to Fc receptors.

Alternative names

SRB1, CLA-1, CD36 antigen-like 1, SR-BI, SCARB1

Technical specifications

  • Antigen: CD36L1 (SR-BI)
  • Clone: REA716
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: SRB1, CLA-1, CD36 antigen-like 1, SR-BI, SCARB1
  • Entrez Gene ID: 949
  • Molecular mass of antigen [kDa]: 61
  • Distribution of antigen: macrophages, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Selected references

    1. Scarselli, E. et al. (2002) The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21(19): 5017-5025
    2. Zeisel, M. B. et al. (2007) Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81. Hepatology 46(6): 1722-1731
    3. Valacchi, G. et al. (2011) Scavenger receptor class B type I: a multifunctional receptor. Ann. N. Y. Acad. Sci. 1229
Product options: 4
130-111-423

CD36L1 (SR-BI)-PE, human

for 30
tests
(1)
-
130-111-236

CD36L1 (SR-BI)-PE, human

for 100
tests
(1)
-
130-111-424

CD36L1 (SR-BI)-APC, human

for 30
tests
(1)
-
130-111-237

CD36L1 (SR-BI)-APC, human

for 100
tests
(1)
-

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