CD357 (GITR) antibodies, mouse

CD357 (GITR) antibodies, mouse

Clone: DTA-1 | Dilution: 1:10
Clone DTA-1 specifically recognizes mouse CD357, also known as glucocorticoid-induced TNF-receptor (GITR) or TNFRSF18, a member of the TNF receptor superfamily. It is expressed at low levels on resting T lymphocytes and at high levels on CD4
+
CD25
+
regulatory T cells (Tregs). Activation of T cells upregulates GITR expression. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation. GITR plays an important role in the function of CD4
+
CD25
+
Tregs.

Alternative Names

TNFRSF18, AITR

Technical specifications

  • Antigen: CD357 (GITR)
  • Clone: DTA-1
  • Isotype: rat IgG2bκ
  • Isotype control: Rat IgG2b – isotype control antibodies
  • Alternative names of antigen: TNFRSF18, AITR
  • Entrez Gene ID: 21936
  • Molecular mass of antigen [kDa]: 23
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, pure
Product options: 3

Product information

Size
Order no.
Price

CD357 (GITR)-PE, mouse

  • DTA-1
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-428
-

CD357 (GITR)-APC, mouse

  • DTA-1
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-389
-

CD357 (GITR) pure, mouse

  • DTA-1
  • For research use only
100 µg in 1 mL
130-092-630
-

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