CD355 (CRTAM) antibodies, mouse

CD355 (CRTAM) antibodies, mouse

Clone: REA882 | Dilution: 1:50
Clone REA882 recognizes the mouse CD355 antigen, also known as class I MHC-restricted T cell associated molecule (CRTAM). CD355 is a type I immunoglobulin-superfamily transmembrane receptor, which is expressed by activated CD8
+
T cells and NK cells, but it is also found on spleen, brain, and testis. CD355 recognizes nectin-like molecule 2 (Necl-2), a cell-surface protein that mediates epithelial cell junctions and interactions with other nectins and Necls. In association with Necl-2, CD355 promotes cytotoxicity of NK cells and IFN-γ secretion of CD8
+
T cells and NK cell–mediated rejection of tumors.
Additional information: Clone REA882 displays negligible binding to Fc receptors.

Alternative Names

CRTAM

Technical specifications

  • Antigen: CD355 (CRTAM)
  • Clone: REA882
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CRTAM
  • Entrez Gene ID: 54698
  • Molecular mass of antigen [kDa]: 42
  • Distribution of antigen: T cells, NK cells, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected References

    1. Kennedy, J. et al. (2000) A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). J. Leukoc. Biol. 67(5): 725-734
    2. Boles, K. S. et al. (2005)
      The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8
      +
      T-cell responses through the cell-surface receptor CRTAM.
      Blood 106: 779-786
    3. Yeh, J. H. et al. (2008) Regulation of a late phase of T cell polarity and effector functions by Crtam. Cell 132(5): 846-859
Product options: 11
130-114-625

CD355 (CRTAM)-FITC, mouse

30 µg in 200 µL (1)
-
130-114-434

CD355 (CRTAM)-FITC, mouse

150 µg in 1 mL (1)
-
130-114-626

CD355 (CRTAM)-PE, mouse

30 µg in 200 µL (1)
-
130-114-435

CD355 (CRTAM)-PE, mouse

150 µg in 1 mL (1)
-
130-114-627

CD355 (CRTAM)-APC, mouse

30 µg in 200 µL (1)
-
130-114-436

CD355 (CRTAM)-APC, mouse

150 µg in 1 mL (1)
-
130-114-628

CD355 (CRTAM)-PE-Vio770, mouse

30 µg in 200 µL (1)
-
130-114-437

CD355 (CRTAM)-PE-Vio770, mouse

150 µg in 1 mL (1)
-
130-114-629

CD355 (CRTAM)-APC-Vio770, mouse

30 µg in 200 µL (1)
-
130-114-624

CD355 (CRTAM)-Biotin, mouse

30 µg in 200 µL (1)
-
130-114-433

CD355 (CRTAM)-Biotin, mouse

150 µg in 1 mL (1)
-