CD353 (SLAMF8) antibodies, human

CD353 (SLAMF8) antibodies, human

Clone: REA394 | Dilution: 1:11
Clone REA394 recognizes the human CD353 antigen, a single-pass type I membrane protein, which is also known as SLAM family member 8 (SLAMF8) or B-lymphocyte activator macrophage (BLAME). CD353 is an immunoglobulin superfamily protein that is a member of the SLAM/CD150/CD2 family of receptors. It is expressed in lymphoid tissue and, more specifically, in some populations of professional APCs, activated monocytes, DCs, and upon activation of macrophages by interferon gamma (IFN-γ) or bacteria. CD353 may play a role in B lineage commitment and/or modulation of signal through the B cell receptor.
Additional information: Clone REA394 displays negligible binding to Fc receptors.

Alternative Names


Technical specifications

  • Antigen: CD353 (SLAMF8)
  • Clone: REA394
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: SLAMF8, BLAME, SBBI42
  • Entrez Gene ID: 56833
  • Molecular mass of antigen [kDa]: 29
  • Distribution of antigen: dendritic cells, monocytes, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
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