CD35 antibodies, human

CD35 antibodies, human

Clone: REA1133 | Dilution: 1:50
Clone REA1133 recognizes the human cell surface protein CD35, the C3b/C4b receptor, also known as CR1 or complement receptor type I. Four CD35 allotypes with different molecular weights are known; 190, 220, 250, and 280 kDa. CD35 is expressed on hematopoietic cells such as granulocytes, monocytes, B cells, subsets of NK and T cells, erythrocytes, and follicular dendritic cells (DCs). Known functions of CD35 include transport of C3 complexes on erythrocytes, complement activation, phagocytosis, and inhibition of the activation-induced proliferation of T and B cells.
Additional information: Clone REA1133 displays negligible binding to Fc receptors.

Alternative Names

CR1, C3BR, C4BR, KN, C3b/C4b-R

Technical specifications

  • Antigen: CD35
  • Clone: REA1133
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CR1, C3BR, C4BR, KN, C3b/C4b-R
  • Entrez Gene ID: 1378
  • Molecular mass of antigen [kDa]: 220
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    cynomolgus monkey (
    Macaca fascicularis
    chimpanzee (
    Pan troglodytes
    olive baboon (
    Papio anubis
  • Distribution of antigen: dendritic cells, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, VioBright 515, Biotin
Product options: -

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