CD337 (NKp30) antibodies – functional grade, human

CD337 (NKp30) antibodies – functional grade, human

Clone: AF29-4D12
Clone AF29-4D12 recognizes the CD337 (NKp30) antigen, a 30 kDa type I membrane glycoprotein characterized by a single V-type Ig-like domain in the extracellular portion. It is found almost exclusively on the surface of resting or activated natural killer (NK) cells. CD337 (NKp30) is a member of the natural cytotoxicity receptors (NCRs) that also include CD335 (NKp46) and CD336 (NKp44), which are responsible for NK cell activation in the process of natural cytotoxicity.
Lytic activity of NK cells could be inhibited to varying degrees by using CD337 (NKp30) antibodies in
in vitro
cytolytic assays, and to a greater degree in combination with CD335 (NKp46) and CD336 (NKp44) antibodies.

Applications

The CD337 (NKp30) functional grade antibody is suited for functional assays, for example,
in vitro
NK cell activation.

Alternative Names

NCR3, 1C7, LY117, MALS, NKp30

Technical specifications

  • Antigen: CD337 (NKp30)
  • Clone: AF29-4D12
  • Isotype: mouse IgG1
  • Alternative names of antigen: NCR3, 1C7, LY117, MALS, NKp30
  • Entrez Gene ID: 259197
  • Molecular mass of antigen [kDa]: 20
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: NK cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
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