CD325 (N-Cadherin) antibodies, human and mouse

CD325 (N-Cadherin) antibodies, human and mouse

Clone: 8C11 | Dilution: 1:50
Clone 8C11 recognizes the human and mouse CD325, also known as cadherin-2 or N-cadherin. CD325, an integral adhesion glycoprotein, consists of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CD325 is a member of cadherins, which are involved in cell adhesion, forming adherens junctions. This is mediated by the extracellular domains of cadherins, whereas the intracellular cytoplasmic tail associates with different adaptor and signaling proteins. The activity of CD325 depends on protein-protein interactions and phosphorylation/dephosphorylation actions.

Alternative Names

Cadherin-2, CDw325, Neural cadherin, N-cadherin

Technical specifications

  • Antigen: CD325 (N-Cadherin)
  • Clone: 8C11
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Cadherin-2, CDw325, Neural cadherin, N-cadherin
  • Entrez Gene ID: 1000, 12558
  • Molecular mass of antigen [kDa]: 82
  • Distribution of antigen: endothelial cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC

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