CD314 (NKG2D) antibodies, human

CD314 (NKG2D) antibodies, human

Clone: REA797 | Dilution: 1:50
Clone REA797 recognizes CD314 (NKG2D), a cell surface receptor of the type II transmembrane receptor NKG2 family. It is expressed on NK cells, CD8
+
α/β T cells, and γ/δ T cells. Though NKG2D itself possesses no intrinsic signaling capability, ligand engagement while associated to the adaptor proteins DAP10 or DAP12 induces cytolytic activation in NK cells as well as costimulation in certain T cell populations. Ligands for NKG2D are stress-inducible MHC class I–related MICA, MICB, and UL16–binding proteins, expressed predominantly on epithelial cells and numerous carcinomas.
Additional information: Clone REA797 displays negligible binding to Fc receptors.

Alternative Names

Klrk1, KLR, NKG2D

Technical specifications

  • Antigen: CD314 (NKG2D)
  • Clone: REA797
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Klrk1, KLR, NKG2D
  • Entrez Gene ID: 22914
  • Molecular mass of antigen [kDa]: 25
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, VioBright 515, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD314 (NKG2D)-PE, human

  • REA797
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-723
-

CD314 (NKG2D)-PE, human

  • REA797
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-645
-

CD314 (NKG2D)-APC, human

  • REA797
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-999
-

CD314 (NKG2D)-APC, human

  • REA797
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-846
-

CD314 (NKG2D)-PE-Vio615, human

  • REA797
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-727
-

CD314 (NKG2D)-PE-Vio615, human

  • REA797
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-649
-

CD314 (NKG2D)-PE-Vio770, human

  • REA797
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-724
-

CD314 (NKG2D)-PE-Vio770, human

  • REA797
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-646
-

CD314 (NKG2D)-VioBright 515, human

  • REA797
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-725
-

CD314 (NKG2D)-VioBright 515, human

  • REA797
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-647
-

CD314 (NKG2D)-Biotin, human

  • REA797
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-722
-

CD314 (NKG2D)-Biotin, human

  • REA797
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-644
-

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