CD300f (IREM-1) antibodies, human

CD300f (IREM-1) antibodies, human

Clone: UP-D2 | Dilution: 1:50
The monoclonal antibody UP-D2 reacts with human CD300f, also known as immune receptor expressed by myeloid cell 1 (IREM-1) which is a type I transmembrane glycoprotein member of the CD300 family. It is expressed on myeloid cells and in peripheral blood on monocytes and granulocytes. IREM-1 binds the p85α regulatory subunit of phosphoinositide 3-kinase (PI3K) and can enhance phagocytosis of apoptotic cells.

Alternative names

CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Technical specifications

  • Antigen: CD300f (IREM-1)
  • Clone: UP-D2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM
  • Entrez Gene ID: 146722
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: myeloid cells, granulocytes, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
  • Selected references

    1. Álvarez-Errico, D. et al. (2007) The IREM-1 (CD300f) inhibitory receptor associates with the p85α subunit of phosphoinositide 3-kinase. J. Immunol. 178: 808-816
    2. Choi, S. C. et al. (2011) Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J. Immunol. 187(7): 3483-3487
    3. Álvarez-Errico, D. et al. (2004) IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Eur. J. Immunol. 34(12): 3690-3701
Product options: 2
130-118-473

CD300f (IREM-1)-PE, human

for 30
tests
(1)
-
130-118-334

CD300f (IREM-1)-PE, human

for 100
tests
(1)
-