CD300e (IREM-2) antibodies, human

CD300e (IREM-2) antibodies, human

Clone: REA1070 | Dilution: 1:50
Clone REA1070 recognizes the human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells. CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs.
Additional information: Clone REA1070 displays negligible binding to Fc receptors.

Alternative Names

CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6

Technical specifications

  • Antigen: CD300e (IREM-2)
  • Clone: REA1070
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6
  • Entrez Gene ID: 342510
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: dendritic cells, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Aguilar, H. et al. (2004) Molecular characterization of a novel immune receptor restricted to the monocytic lineage. J. Immunol. 173: 6703-6711
    2. Brckalo, T. et al. (2010) Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells. Eur. J. Immunol. 40(3): 722-732
Product options: 22
130-118-853

CD300e (IREM-2)-FITC, human

for 30
tests
(1)
-
130-118-795

CD300e (IREM-2)-FITC, human

for 100
tests
(1)
-
130-118-854

CD300e (IREM-2)-PE, human

for 30
tests
(1)
-
130-118-796

CD300e (IREM-2)-PE, human

for 100
tests
(1)
-
130-118-855

CD300e (IREM-2)-APC, human

for 30
tests
(1)
-
130-118-797

CD300e (IREM-2)-APC, human

for 100
tests
(1)
-
130-118-856

CD300e (IREM-2)-VioBlue, human

for 30
tests
(1)
-
130-118-798

CD300e (IREM-2)-VioBlue, human

for 100
tests
(1)
-
130-118-857

CD300e (IREM-2)-VioGreen, human

for 30
tests
(1)
-
130-118-799

CD300e (IREM-2)-VioGreen, human

for 100
tests
(1)
-
130-118-858

CD300e (IREM-2)-PE-Vio615, human

for 30
tests
(1)
-
130-118-800

CD300e (IREM-2)-PE-Vio615, human

for 100
tests
(1)
-
130-118-859

CD300e (IREM-2)-PE-Vio770, human

for 30
tests
(1)
-
130-118-801

CD300e (IREM-2)-PE-Vio770, human

for 100
tests
(1)
-
130-118-860

CD300e (IREM-2)-APC-Vio770, human

for 30
tests
(1)
-
130-118-802

CD300e (IREM-2)-APC-Vio770, human

for 100
tests
(1)
-
130-118-861

CD300e (IREM-2)-PerCP-Vio700, human

for 30
tests
(1)
-
130-118-803

CD300e (IREM-2)-PerCP-Vio700, human

for 100
tests
(1)
-
130-118-862

CD300e (IREM-2)-VioBright 515, human

for 30
tests
(1)
-
130-118-804

CD300e (IREM-2)-VioBright 515, human

for 100
tests
(1)
-
130-118-863

CD300e (IREM-2)-Biotin, human

for 30
tests
(1)
-
130-118-805

CD300e (IREM-2)-Biotin, human

for 100
tests
(1)
-