CD30 antibodies, human

CD30 antibodies, human

Clone: REA1085 | Dilution: 1:50
Clone REA1085 recognizes the human CD30 antigen, a cell membrane protein, which is a member of the tumor necrosis factor receptor (TNFR) superfamily, and also known as Ki-1. CD30 is used as a tumor marker and is found on Hodgkin/Reed-Sternberg (H/RS) cells, embryonal carcinoma cells, and on activated T and B lymphocytes. It functions as a receptor for TNFSF8/CD30L and is involved in the regulation of cellular growth and transformation of activated lymphoblasts and regulates signal transduction by activation of NF-κB.
Additional information: Clone REA1085 displays negligible binding to Fc receptors.

Alternative Names

TNFRSF8, Ki-1, Ber-H2

Technical specifications

  • Antigen: CD30
  • Clone: REA1085
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TNFRSF8, Ki-1, Ber-H2
  • Entrez Gene ID: 943
  • Molecular mass of antigen [kDa]: 62
  • Distribution of antigen: B cells, T cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected References

    1. Lee, S. Y. et al. (1996) T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors. J. Exp. Med. 183(2): 669-674
    2. Aizawa, S. et al. (1997) Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation. J. Biol. Chem. 272(4): 2042-2045
    3. Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794
Product options: 20
130-118-436

CD30-FITC, human

for 30
tests
(1)
-
130-118-282

CD30-FITC, human

for 100
tests
(1)
-
130-118-437

CD30-PE, human

for 30
tests
(1)
-
130-118-283

CD30-PE, human

for 100
tests
(1)
-
130-118-438

CD30-APC, human

for 30
tests
(1)
-
130-118-284

CD30-APC, human

for 100
tests
(1)
-
130-118-439

CD30-VioBlue, human

for 30
tests
(1)
-
130-118-285

CD30-VioBlue, human

for 100
tests
(1)
-
130-118-440

CD30-PE-Vio615, human

for 30
tests
(1)
-
130-118-286

CD30-PE-Vio615, human

for 100
tests
(1)
-
130-118-441

CD30-PE-Vio770, human

for 30
tests
(1)
-
130-118-287

CD30-PE-Vio770, human

for 100
tests
(1)
-
130-118-442

CD30-APC-Vio770, human

for 30
tests
(1)
-
130-118-288

CD30-APC-Vio770, human

for 100
tests
(1)
-
130-118-443

CD30-PerCP-Vio700, human

for 30
tests
(1)
-
130-118-289

CD30-PerCP-Vio700, human

for 100
tests
(1)
-
130-118-444

CD30-VioBright 515, human

for 30
tests
(1)
-
130-118-290

CD30-VioBright 515, human

for 100
tests
(1)
-
130-118-445

CD30-Biotin, human

for 30
tests
(1)
-
130-118-291

CD30-Biotin, human

for 100
tests
(1)
-